Two laboratory methods for diagnosis of herpes simplex keratitis.

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Two laboratory methods for diagnosis of herpes simplex keratitis.

Two techniques are described which enable a rapid diagnosis of herpes simplex keratitis to be made. The tests, antibody/antigen reactions, were shown to be accurate and sensitive in the 119 patients examined. A result is available within four hours with the indirect peroxidase-antiperoxidase method and within one hour with the direct method. The techniques are relatively inexpensive, though lab...

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Epidemiology of Herpes Simplex Keratitis.

Considerable information has been accumulated concerning the herpes virus and its relationship to man, its natural host (Table VI). It is evident that to control the diseases produced, by the virus it is essential that some means be found not only to control the acute manifestations but also to eliminate the harbored virus from the readily available supply in the numerous ubiquitous carriers. A...

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Herpes Simplex Keratitis: Bilateral Effects.

Müller et al. studied corneal nerve morphology and endothelial cell density (ECD) in patients with and without unilateral herpes simplex keratitis (HSK). They demonstrated correlated reductions in corneal central ECD, subbasal nerve number and length, and sensation in both the affected and clinically unaffected contralateral eyes. They suggest a potential link between corneal innervation and en...

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Herpes simplex keratitis in children.

Ophthalmic findings are reported in 31 eyes of 28 children with herpes simplex keratitis. Twenty two had dendritic ulcers, and nine had geographic ulcers or disciform stromal keratitis. After resolution of keratitis, 80% (19/22) of children with dendritic ulcers achieved corrected visual acuity of 6/9 or better, 50% (11/22) had induced astigmatism, 45% (9/22) had one to five recurrences. In the...

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Herpes simplex keratitis: challenges in diagnosis and clinical management

Herpes simplex virus is responsible for numerous ocular diseases, the most common of which is herpetic stromal keratitis. This is a recurrent infection of the cornea that typically begins with a subclinical infection of the cornea that establishes a latent infection of sensory ganglia, most often the trigeminal ganglia. Recurring infections occur when the virus is reactivated from latency and t...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1987

ISSN: 0007-1161

DOI: 10.1136/bjo.71.10.742